Dr. Luna Goswami
Associate Professor
Ph.D Max Planck Institute, Humboldt University, Berlin, Germany
M. Tech in Polymer Science & Technology, University of Calcutta, India


Email : [email protected]

Post-Doctoral Experience

Max Planck Institute of Colloids & Interfaces,Degree awarded from Humboldt University, Department of Organic & Bio-Organic Chemistry, Berlin, Germany,2009

Awards/Honours

  1. Research Fellowship (Austrian and institutional fellowship) for PhD study from Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Potsdam, Germany, 2004.
  2. Junior Research Fellowship in Engineering & Technology from University Grants Commission, Delhi University, New Delhi-110 021, India, 2003.
  3. Senior research fellowship under National Agricultural Technology Project, 2002.
  4. Stood first class first in M.Tech. Examination from University of Calcutta, 2002.

Current Research Activity

Our group is mainly working on synthesis and characterization of several new biomaterials (such as hydrogels, nanocomposites, etc) and aim to apply these materials for biomedical applications. At present we are synthesizing different natural polymeric compound-based hydrogels in combination with inorganic nanofillers. Various natural polymers like starch, cellulose etc. and natural biomaterials like gelatin, agar, bahera etc are explored for this purpose. Physical and chemical modification of both natural biomaterials and fillers is a realistic option to facilitate proper filler-matrix interactive mixing and achievement of desired gel- characteristics. Our lab routinely characterizes gelation and interaction through viscometric measurements and other techniques such as optical microscopy, SEM/TEM, X-ray diffraction, GC-MS, FT-IR spectroscopy, Raman spectroscopy etc. All these allow us to understand the morphology of gels and nanocomposites. Finally, these hydrogels and nanocomposites are subject to test for their drug release abilities against different cells. We use different microscopic techniques and fluorescence activated cell sorter (FACS) measurements to analyze the effects of the delivered drugs. We aim to apply these hydrogels and nanocomposites for tissue engineering applications. Therefore these materials may have clinical as well as commercial applications in future.

The other focus areas of the lab work are to identify novel microbes for unique enzymes and characterization of lipid-protein interaction by different spectroscopic methods.

Selected Publications

Full List
  1. Sanyasi S, Kumar A, Goswami C, Bandyopadhyay A, Goswami L* (2014) Synthesis and characterization of a novel polysaccharide based extracellular matrix for efficient adhesion and growth of osteoclast-precursor cells. Carbohydrate Polymer, 101, 1033-1042.
  2. Giri A, Bhunia T, Mishra SR, Goswami L, Panda AB, Pal S, Bandyopadhyay A.(2013) Acrylic acid grafted guargum-nanosilica membranes for transdermal diclofenac delivery. Carbohydr Polym., 91, 492-501.
  3. Goswami L., Dunlop J.W.C., Jungnikl K., Eder M., Gierlinger N., Coutand C., Jeronimidis G., Fratzl P., Burgert I. (2008) Stress generation in tension wood of poplar is based on the lateral swelling power of the G-layer. The plant Journal, 56, 531-538.
  4. Goswami L., Eder M., Gierlinger N., Burgert I. (2008) Inducing large deformation in wood cell walls by enzymatic modification. Journal of Material Science, 43, 1286-1291.
  5. Gierlinger N., Goswami L., Schmidt M., Burgert I., Coutand C., Rogge T., Schwanninger M. (2008) In-situ FT-IR microscopic study on enzymatic treatment of poplar wood cross-sections. Biomacromolecules, 9, 2194-201.

Research interest and special topics:

  • Preparation and characterization of different hydrogels for bone tissue engineering and controlled drug delivery system
  • Isolation, characterization and commercial application of the novel enzymes and usage of these enzymes for characterization of biopolymers
  • Analysis of the biomaterials by using different spectroscopic and microscopic techniques
  • Lipid-protein interactions

Research activities:

Sponsored Projects

  • As PI: Title:Screening, purification, molecular cloning and functional characterization of the novel plant cell wall-degrading enzymes from natural sources”. Sponsored by DST (19 Lakhs). Year -2012-2015
  • As Co-PI: Title: “Regulation of cytoskeletal components by TRPV receptors and vice versa relevant in cancer and neuropathic pain”. Approved and waiting for fund release from DST. (15 Lakh). Year 2013-2015
  • As PI: Title: “Synthess and charaterisaton of novel hydrogels for adhesion of cells for potental applaton in bone tisse engineering from ICMR. (35 Lakh).
  • As PI:Title:“Development of De-metalizer Kit from Biopolymers for Efficient Removal of Heavy Metal Ions from Contaminated Water Especially of the Mining Areas” from DBT (BIRAC). (40.6 Lakhs). Year -2015-2016
  • Mr.Sridhar Sanyasi (Ph.D Scholar)
    Synthesis and characteristics of different polymeric composites for biomedical applications.
    [email protected]
  • Mr.Satish Kumar (Ph.D Scholar)
    Preparation and characteristics of novel hydrogels for bone tissue engineering.
    [email protected]
  • Ms. Priyanka Choudhury (Ph.D Scholar)
    Synthesis and characteristics of different biomaterials for skin tissue engineering.
    [email protected]
  • Ms.Navneet kaur
    M.tech trainee
  1. Goswami L., Dunlop J.W.C., Jungnikl K., Eder M., Gierlinger N., Coutand C., Jeronimidis G., Fratzl P., Burgert I. (2008)Stress generation in tension wood of poplar is based on the lateral swelling power of the G-layer. The plant Journal,56, 531-538.
  2. Goswami L., Eder M., Gierlinger N., Burgert I. (2008) Inducing large deformation in wood cell walls by enzymatic modification. Journal of Material Science, 43, 1286-1291.
  3. Gierlinger N., Goswami L.,Schmidt M., Burgert I., Coutand C., Rogge T., Schwanninger M. (2008) In-situ FT-IR microscopic study on enzymatic treatment of poplar wood cross-sections. Biomacromolecules, 9, 2194-201.
  4. Goswami C. and Goswami L. (2010) Filamentous microtubules in the neuronal spinous process and the role of microtubule regulatory drugs in neuropathic pain. Neurochemistry International,57, 497-503.
  5. Gupta B., Banerjee D.,Goswami L.,Bandyopadhyay A. (2011) Physicomechanical studies and solvent resistance analysis of melt-blended novel ethylene-1-octene elastomer and ethylene-co-acrylic acid interpenetrating network hybrids. Journal of Applied Polymer Science, 120, 3401–3409,
  6. Bhunia T., Goswami L., Chattopadhyay D., BandyopadhyayA. (2011) Swelling deswellingstudies after freeze-thaw treatment of nano silica reinforced Poly (vinyl alcohol)- based organic-inorganic hybrid hydrogel. International Journal of Nanoscience, 10, 1-4.
  7. Bhunia T., Goswami L., Chattopadhyay D., BandyopadhyayA. (2011)Sustained transdermal release of diltiazem hydrochloride through electron beam irradiated different PVA hydrogel membranes. Nuclear Instruments and Methods in Physics Research B, 269, 1822-1828.
  8. Majhi R, Sardar P, Goswami L,Goswami C. (2011) Right time - right location - right move: TRPs find motors for common functions. Channels, 5, 375-381.
  9. Pervin R., Goswami L., Vijayabaskar V.,Bandyopadhyay A.(2012) Understanding engineering properties of high octene grade poly (ethylene-co-1-octene)-poly (ethylene-co-vinyl acetate) interpenetrating network blends through Taguchi design of experiment (DOE). Journal of Applied Polymer Science, 126, 1993–2003.
  10. Basak G.C., Goswami L.,Bandyopadhyay A. (2012) A completely new technique of plasticizing atactic polystyrene by chrome tanned waste leather buffing dust in its composites., Polymer and polymer composites20, 279-288.       .
  11. Giri A, Bhunia T, Mishra SR, Goswami L, Panda AB, Pal S, Bandyopadhyay A.(2013)Acrylic acid grafted guargum-nanosilica membranes for transdermal diclofenac delivery. CarbohydrPolym., 91, 492-501. (The content of this manuscript was selected to make story in Nature India, the Indian group of the Nature Group of Journals)
  12. Kumar A, Goswami L, GoswamiC. (2013) Importance of TRP channels in stress and pain. Frontiers in Bioscience, 5, 19-38.
  13. Majhi R K, Kumar A, Yadav M, Swain N, Kumari S, Saha A, Pradhan A, Goswami L, Saha S, Samanta L, Maity A, Nayak TK, Chattopadhyay S, Kumar A, Goswami C. (2013) Endogenous expression of thermo-sensitive ion channel TRPV1 in the sperm cells of a fresh water living fish (Labeorohita). Channels, 7.
  14. Sanyasi S, Kumar A, Goswami C, Bandyopadhyay A, Goswami L*(2014) Synthesis and characterization of a novel polysaccharide based extracellular matrix for efficient adhesion and growth of osteoclast-precursor cells. Carbohydrate Polymer,101, 1033-1042.
  15. Pervin R., MondalS.,Goswami L., Vijayabaskar V.,Bandyopadhyay A.(2014) Statistically Designed High and Low Methyl Acrylate (MA) Containing EMA-Ethylene-Octene Copolymer Double Network Hybrids: Interesting Contrast in Physico-mechanical, Rheological and Electrical Properties. Polymer and polymer composites (accepted).
  16. Giri A, Mishra SR, Goswami L, Panda AB,Bandyopadhyay A. A transdermal device from 2- hydroxy ethyl methacrylate grafted carboxymethyl guar gum- multiwalled carbon nanotube composites (2014), RSC advances, 4, 13546-13556.
  17. Nasim T, Pal A, Giri A, Goswami L, Bandyopadhyay A. Exploring polyelectrolytic feature of the extruded from native acasianilotica for flocculating aqueous fouling suspension (2014), Separation and Purification Technology,131, 50-59.
  18. Giri A,Bhunia T, Goswami L, Panda AB, Bandyopadhyay A. Fabrication of acrylic acid grafted guar gum multiwalled carbon nanotube hydrophobic membranes for transdermal drug delivery (2015), RSC Advances,5, 41736–41744
  19. Majhi RK, Saha S, Kumar A,Ghosh A, Swain N, Goswami L, Mohapatra PP, Maity A, Sahoo V, Kumar A, Goswami C.(2015) Sperm specific expression of temperature-sensitive ion channel TRPM8 correlates with vertebrate evolution. PeerJ3:e1310.
  20. Giri A, Goswami L, Bandyopadhyay A (2015). In-situ synthesis of acrylate grafted carboxymethylguargum-carbon nanotube membranes for potential application in controlled drug delivery, European Polymer Journal, 74, 13-25.
  21.  Sanyasi S,  Majhi R K, Kumar S, Mishra M, Ghosh A,  Satyam P V, Mohapatra H,  Goswami C, Goswami L* (2016) Polysaccharide-capped silver Nanoparticles inhibit biofilm formation and eliminate multi-drug-resistant bacteria by disrupting bacterial cytoskeleton with reduced cytotoxicity towards mammalian cells, Scientific reports , 6, 24929