Dr. Selvakumar Elangovan
Assistant Professor
Ph. D. University of Madras, Chennai, India. (2006)
M. Sc. University of Madras, Chennai, India. (2002)


Email:
[email protected]

Post-Doctoral Training

  • Department of Biochemistry and Molecular Biology, Georgia Health Sciences University (now Georgia Regents University), Augusta, GA, USA. (2008-2012)
  • Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY, USA. (2006-2008)

Awards/Honors

  • Junior Research Fellowship (JRF) award from Indian Council of Medical Research (ICMR), New Delhi, India. (2002)
  • Senior Research Fellowship (SRF) award from Indian Council of Medical Research (ICMR), New Delhi, India. (2004)

Research Interest

  • Estrogen receptor signalling in breast cancer
  • TGFβ signalling in breast cancer metastasis
  • Chemoprevention of breast cancer

Selected Publications

Full List
  1. Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Lan L, Singh N, Martin PM, Hawthorn L, Prasad PD, Ganapathy V, Thangaraju M. The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival. Cancer Res. 2014;74:1166-78.
  2. Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M. Molecular mechanism of SLC5A8 inactivation in breast cancer. Mol Cell Biol. 2013;33:3920-35.
  3. Coothankandaswamy V, Elangovan S, Singh N, Prasad PD, Thangaraju M, Ganapathy V. The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function. Biochem J. 2013;450:169-78.
  4. Elangovan S, Ramachandran S, Venkatesan N, Ananth S, Gnana Prakasam JP, Martin PM, Browning DD, Schoenlein PV, Prasad PD, Ganapathy V, Thangaraju M. SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer. Cancer Res. 2011;71:6654-64.
  5. Selvakumar E, Hsieh TC. Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by lipoic acid: role in cancer prevention and therapy. J Hematol Oncol. 2008;1:4.