Srinivas Patnaik
Dean & Professor
Dr. Srinivas Patnaik earned his MSc in Biotechnology from Goa University and PhD from Institute of Life sciences, Bhubaneswar specialised in “Molecular Oncology”. Presently, Dr. Patnaik is working as an Professor and Dean in School of Biotechnology, KIIT University. Dr. Patnaik conferred the young scientist by Department of Science and Technology, Odisha and have received STA fellowship from IARC, World Health Organisation, Lyon, France. Dr. Patnaik, had 12-year experience working in USA and Europe with eminent scientists in the field of DNA repair and cancer. He has published research articles in high impact journals such as Gastroenterology, Cancer Research, Oncogene, Nucleic Acid Research to name a few. Dr. Patnaik has been member of several national and international scientific societies and is actively serving in the review board in many international journals such cancer letters, Scientific Reports, Cellular and Molecular Biochemistry etc. Apart from research, Dr. Patnaik has been a passionate teacher and involved in teaching molecular biology, genetic engineering and cell biology. In addition to the core topics he is interested and involved in teaching soft skills such as "personality development and scientific writing" to final year M Tech and MSc students. Currently his research group is working in the field of gastrointestinal inflammation and colorectal cancer using genetically modified mouse models.
Profile Links
Email :
[email protected]
Scopus Id :
7102590490
Google Scholar :
https://scholar.google.com/citations?user=E_f-JdwAAAAJ&hl=en
Social Links
Ph.D.
Projects
Principal Investigator
- Validation of anti-cancer activity of phytochemicals from traditional herbal healing practices. National Innovation Foundation, DST. Completed: 31-03-2020
- Design and Evaluation of novel formulations of some anti- cancer drugs for metronomic chemotherapy BIG Grant, BIRAC, Department of Biotechnology, Govt. of India. Completed: 31-01-2017
- Evaluation of antileukemic and immunogenicity properties of engineered Eschericha coli asparaginase-II for the treatment of acute lymphatic leukemia in preclinical model, Department of Science and Technology, Govt. of India. Completed: 27-1-2019
- Multipronged approach for pre-clinical assessment of novel curcumin formulations as drugs for breast cancer therapy. Department of Biotechnology, Govt. of India. Ongoing: 2020-2023
- Understanding the enigma of interconnection between inflammatory bowel disease (IBD) and neurodegeneration utilizing genetically predisposed IBD mice model, Department of Health Research, ICMR. Ongoing: 2020-2023
Administrative Responsibility
Dean
Awards & Honours
- World Health Organisation (WHO) Fellowship (STA) for pursuing research on cancer at International Agency for Research on Cancer, IARC, Lyon, France. 2002
- Orissa Young Scientist Award, Department of Science and Technology, Orissa, India. 2000
- Senior Research Scholarship award by UGC, India. 1998
- Junior Research Scholarship award by UGC, India. 1996
- National Scholarship awarded by Department of Biotechnology, India. 1994
Memberships
- Associate Member: American Association for Cancer Research (AACR)
- Associate Member: American Gastroenterological Association (AGA)
- Life Member: Indian Association for Cancer Research (IACR) Member
- The International Mammalian Genome Society (IMGS)
Outreach Activity
Serving as reviewer in cancer letters, Scientific Reports, Cellular and Molecular Biochemistry. Associate editor journal- Health and Population: Perspectives and Issues (HPPI)
1. Srinivas Patnaik* and Anupriya. Drugs Targeting Epigenetic Modifications and Plausible Therapeutic Strategies Against Colorectal Cancer. Front. Pharmacol.06 June 2019. https://doi.org/10.3389/fphar.2019.00588
2. Srivastava AK, Banerjee A, Cui T, Han C, Cai S, Liu L, Wu D, Cui R, Li Z, Zhang X, Xie G, Selvendiran K, Patnaik S, Karpf AR, Liu J, Cohn DE, Wang QE. Inhibition of miR-328-3p Impairs Cancer Stem Cell Function and Prevents Metastasis in Ovarian Cancer. Cancer Res. 2019 May 1;79(9):2314-2326
3. Roy S, Esmaeilniakooshkghazi A, Patnaik S, Wang Y, George SP, Ahrorov A, Hou JK, Herron AJ, Sesaki H, Khurana S. Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation. Gastroenterology. 2018 Apr;154(5):1405-1420
4. Patnaik S, George SP, Pham E, Swati R, Singh K, Mariadason JM, Khurana S. By moonlighting in the nucleus villin regulates epithelial plasticity. Mol Biol Cell. 2015 Dec 10.
5. Wang Y, George SP, Srinivasan K, Patnaik S and Khurana S. Actin reorganization as the molecular basis for the regulation of apoptosis in gastrointestinal epithelial cells. Cell death and differentiation. 2012 Sep; 19 (9):1514-24.
6. Wang QE, Praetorius-Ibba M, Zhu Q, El-Mahdy MA, Wani G, Zhao Q, Qin S, Patnaik S, Wani AA. Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair. Nucleic Acids Res. 2007; 35(16):5338-50.
7. Zhu Q, Wani G, Yao J, Patnaik S, Wang QE, El-Mahdy MA, Praetorius-Ibba M, Wani AA. The ubiquitin-proteasome system regulates p53-mediated transcription at p21waf1 promoter .Oncogene. 2007 Jun 21; 26(29):4199-208.
8. Yang YG, Cortes U, Patnaik S, Jasin M and Wang ZQ. Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene 2004 Mar 15.
9. Nagpal JK, Patnaik S, Das BR. Prevalence of high-risk human papilloma virus types and its association with P53 codon 72 polymorphism in tobacco addicted oral squamous cell carcinoma (OSCC) patients of Eastern India. Int J Cancer. 2002 Feb 10; 97(5): 649-53.
10.Patnaik S, Nayak BK, Das BR. Rearrangement in the coding and 5' region of p53 gene in human oral tumors. IUBMB Life. 1999 Sep; 48(3): 305-9.
Books :
Nanomedicine; Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering